• It is recommended that pilsicainide be administered

  2019-06-18

  

  It is recommended that pilsicainide be administered over 10min, with 1.0mg/kg being the maximum daily dosage allowed. However, a single oral dose of pilsicainide has been shown to be effective, feasible and safe, and the single dose is always from 100 to 150mg [4,10]. Both the time to maximum drug

• It is generally agreed that a previous history of

  2019-06-18

  

  It is generally agreed that a previous history of aborted cardiac arrest, syncope, presence of a spontaneous type-1 ECG, and male gender are significant predictors of further arrhythmic events [5,7,10,11,32,33]. Risk stratification Exercise testing Some clinical studies have reported the augm

• Since many decades bone tumours have stimulated imagination

  2019-06-18

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• br Conflict of interest br Disclosures br

  2019-06-18

  

  Conflict of interest Disclosures Acknowledgments Patient presentation A 64-year-old male with a history of a right ventricular outflow tract ventricular tachycardia (RVOT-VT) ablation presented from an outlying hospital due to four recent episodes of non-exertional syncope. He had three

• Validation study findings showed that knowledge KR had

  2019-06-17

  

  Validation study findings showed that knowledge (KR20=0.58) had moderate internal consistency. Even though this was fairly acceptable, the knowledge domain was considered a good test as KR20 tends to result in more conservative estimates than Cronbach’s alpha [28]. Enhancing the reliability of a que

• Es pertinente mencionar que el enfoque

  2019-06-17

  

  Es pertinente mencionar que el enfoque metodológico desarrollado por la autora nos adentra en las preocupaciones centrales de estos tres intelectuales; nos presenta sus argumentos, su visión de México, del gobierno, de sus instituciones, su pasado y el devenir. De igual forma, se muestra a estos tre

• To the best of our

  2019-06-17

  

  To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t

• In the past two decades

  2019-06-17

  

  In the past two decades, several studies have consistently found that up to one-sixth of cancers worldwide are attributable to infectious pathogens. Cancers caused by infectious agents present unique opportunities for prevention and treatment; therefore, a detailed understanding of how infections co

• While immunogenic action of langerhans cells had

  2019-06-17

  

  While immunogenic action of langerhans SC 79 had thoroughly been illustrated, their tolerogenic action is still being in its infancy stage. Ralph. M. Steinman shared the Nobel Prize in 2011 for his work on dendritic cells and their role in immunity. He uncovered the role of dendritic cells in periph

• We have recently completed a prospective randomized feasibil

  2019-06-17

  

  We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co

• The congruence between BrS and

  2019-06-17

  

  The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope

• br Results Compared to the respective untreated groups

  2019-06-15

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• br Reflexionar sobre esta frase que

  2019-06-15

  

  Reflexionar sobre esta frase, que aparece temprano en , es vislumbrar una versión concentrada del libro entero. Digo bien una versión, pues se podrían expresar otras dinámicas igualmente representativas de la obra al reemplazar las palabras ‘fijeza’ y ‘cambio’ por ‘destrucción’ y ‘renovación’, ‘de

• Por su parte Juan Carlos Grijalva titula su

  2019-06-15

  

  Por su parte, Juan Carlos Grijalva titula su artículo “A caballo, por la ruta de los libertadores: el legado mesiánico y elitista de José Vasconcelos en Ecuador”. Grijalva explica que el ensayista mexicano llegó A-366 manufacturer Ecuador el 17 de junio de 1930 procedente de Colombia, cabalgando los

• br Material and methods br Results br

  2019-06-15

  

  Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of

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