• We report a case of DCML deficiency

  2019-04-30

  

  We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con

• br Other drugs Overdose of diphenhydramine

  2019-04-30

  

  Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium p-Cresyl sulfate and thus to unmask a BrS phenotype [60]

• We observed a downregulation of several thyroid related gene

  2019-04-30

  

  We observed a downregulation of several thyroid-related genes such as DUOX1, DUOX2, TG, and TSHR. This may appear counterintuitive given that dedifferentiation typically worsens patient outcomes. However, it is noteworthy that there was no difference in the betaxolol of SLC5A5 (sodium-iodide sympor

• The aim of this cross

  2019-04-30

  

  The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c

• Sin considerar la poes a de

  2019-04-30

  

  Sin considerar la poesía de Villaurrutia en esta ocasión, es evidente que el pasaje citado representa una elocuente cristalización del su relevancia para el pensamiento y la poética de Octavio Paz. Es notable que el juicio crítico de Paz incluya referencias al universo —donde los opuestos coexisten

• The participants discussed several overarching themes conclu

  2019-04-30

  

  The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc

• En esta l nea los

  2019-04-30

  

  En esta línea, los editorialistas sin la intención de convertirse en los aguafiestas del advenimiento de la República, criticaban las afirmaciones sobre las bondades de la intervención. “Cuba está mucho peor que en 1899. Los gobiernos militares dieron mayor interés purchase Obeticholic Acid la polít

• Desde la perspectiva expuesta la etnicidad constituye una

  2019-04-30

  

  Desde la perspectiva expuesta, la etnicidad constituye una dimensión potencial de la identidad, fundamentada en un conjunto de elementos que, al seguir la tradición weberiana, pueden abarcar la percepción de origen, cultura, idioma o rasgos fenotípicos compartidos por un conjunto de personas. La adq

• O pr prio enfermeiro treinador

  2019-04-30

  

  O próprio enfermeiro-treinador não pode ir embora por temer o destino dos cães, diz, se o homem imóvel resolver fazer uma matança com GSK503 ajuda da central telefônica. A resposta das duas mulheres presentes na casa, a mãe e a irmã [“diante de uma situação desse tipo, se trancariam aterrorizadas em

• br Case report We report a case of

  2019-04-30

  

  Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence

• br In after the publication of a randomised controlled trial

  2019-04-29

  

  In 2012, after the publication of a randomised controlled trial showing that a single oral dose of azithromycin was as effective as intramuscular benzathine benzylpenicillin for the treatment of yaws, WHO launched a new, ambitious initiative—the Morges strategy—for the eradication of the disease b

• Our patients with decreased regional and global contractilit

  2019-04-29

  

  Our patients with decreased regional and global contractility of the LV were older. Similarly, systolic dysfunction correlated with age of patients in several studies, and one large study reported that HF was virtually absent in DM1 patients before the age of 40. On the other hand, systolic dysfunct

• The authors of the NCCN

  2019-04-29

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• br OPG RANK and RANKL contribute

  2019-04-29

  

  OPG, RANK and RANKL contribute to the vicious cycle established between tumour eukaryotic initiation factor and bone microenvironment: evidences for sarcomas and carcinomas In bone microenvironment, OPG/RANK/RANKL molecular triad is not solely expressed by bone cells. Whether OPG is considered as

• In this work we confirmed that MDA

  2019-04-29

  

  In this work we confirmed that MDA-MB-231 breast cancer eph receptor are sensitive to AT-406 by restoring apoptosis in this cell line at nanomolar concentrations [11]. It was previously shown by us and other authors that RANK (receptor activator of NF-κB) is expressed in vitro by several human bre

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