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The aim of the present study was to
2021-08-30
The aim of the present study was to investigate the acute effects of THC on resting state Firefly Luciferase neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI st
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Terbutaline Sulfate br Author contributions br Funding M E
2021-08-30
Author contributions Funding M.E.B. was supported by Research Fund #3096. Competing interests Introduction Lung cancer has become one of the most common death causes in both male and female malignant tumors (Jemal et al., 2011). Air pollution, smoking and estrogen level are known risk f
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To our knowledge this is the first report
2021-08-30
To our knowledge, this is the first report of an oncocytoma expressing alpha-enolase or causing autoimmune retinopathy and optic neuropathy. Although generally considered benign, oncocytomas have rarely been associated with paraneoplastic syndromes, including tumor-induced hypertension, erythrocytos
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Mono and bi ubiquitination of two lysines namely K and
2021-08-30
Mono- and bi-ubiquitination of two lysines, namely K70 and K76, in a small fraction of p33 replication co-factor has been demonstrated in yeast (Barajas and Nagy, 2010, Li et al., 2008). Because mutations of these lysines reduced TBSV repRNA replication in yeast and affected the ability of p33 to in
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br Results and discussion To check the hypothesis that the
2021-08-28
Results and discussion To check the MRS1523 that the charge of α-synuclein can be altered due to the glycation, we measured zeta potential of native α-synuclein and α-synuclein glycated by two different glycating agents, methylglyoxal (MG) and glyceraldehyde-3-phosphate (GA-3-P). The value for n
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It is interesting to note that oligomerization
2021-08-28
It is interesting to note that oligomerization of recombinant DDR1 ECD primarily occurred when the protein was incubated with collagen in solution and to a much lesser extent when collagen was pre-immobilized on a surface as reported in our earlier studies (Agarwal et al., 2007). We believe that pre
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br Conflict of interest statement
2021-08-28
Conflict of interest statement Acknowledgement The study was financially supported by the Ministry of Education, Youth and Sports of the Czech Republic – projects “CENAKVA” (No. CZ.1.05/2.1.00/01.0024) and “CENAKVA II” (No. LO1205 under the NPU I program), by the Grant Agency of the University
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Several evidences showed that seizures increase brain extrac
2021-08-28
Several evidences showed that seizures increase brain extracellular glutamate, which binds to N-methyl-d-aspartate (NMDA) receptor, then up-regulated cyclooxygenase-2 (COX-2) expression in brain capillaries to increase BBB P-gp expression [11,13,29,30]. A recent study demonstrated a different signal
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The associations between genetic factors and socio emotional
2021-08-28
The associations between genetic factors and socio-emotional functioning are complex and almost certainly not direct. They are mediated through a variety of developmental processes including individual differences in personality traits (Davis and Loxton, 2013, Saphire-Bernstein et al., 2011). For th
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Cytochrome Oxidase Activity Colorimetric Assay Kit Fermenta
2021-08-28
Fermentation process for growth of E. coli BL2(DE3)/pBMS–P3Hcys was carried out in 25- and 380-L fermentors containing 15- and 250-L medium, respectively. Cell yield of about 100g/L (wet cells) was achieved by feeding glycerol and Hy-yest during fermentation. Typical fermentation parameters are show
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In a recent study a CMV
2021-08-28
In a recent study, a CMV DNA load cut-off of 500 IU/ml in BAL fluid was found to have a positive predictive value of ∼50% for the presence of probable CMV pneumonia (considering a prevalence of this event of 10% among patients at risk and undergoing BAL testing). Tan et al., in contrast, found CMV D
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Our results for imidacloprid were
2021-08-28
Our results for imidacloprid were unexpected: considering that imidacloprid (Im) is a neonicotinoid insecticide with a different mode of action (agonist of the nicotinic TCS 3035 receptor) than OPs, we expected Es-ChE and T-ChE activity to be largely insensitive to changes in Im concentrations. How
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br Discussion Variable estradiol effects on cell proliferati
2021-08-28
Discussion Variable estradiol effects on cell proliferation have been reported according to animal species, tissues, and type of estrogen receptor [16,21,22,[29], [30], [31]]. In the kidney, 17βE was found to increase [3H]-thymidine incorporation in primary rabbit kidney proximal tubule 487 [30]
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br Introduction Cell transplantation therapies using embryon
2021-08-28
Introduction Cell transplantation therapies using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC)-derived retinal tissue (ESC/iPSC retina) or Balaglitazone mg have emerged as therapeutic options for retinal degeneration following recent breakthroughs. A number of groups have sh
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br Enzyme activations Activated proteinases
2021-08-28
Enzyme activations Activated proteinases can unleash a deluge of tissue damage (Zucker et al., 2009). Once activated, the essential enzymes such as serine proteases and cysteine proteases cannot discriminate between self and non-self, burning away self-tissues (Chien et al., 2009, Laskar et al.,
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