• One of the mechanism of regulation of NO content in

  2022-08-19

  

  One of the mechanism of regulation of NO content in plant cells is it scavenging by GSH leading to formation of GSNO [59]. This reaction, depending on NO level and availability of glutatione in its reduced form, influences cellular redox potential by lowering GSH content and in consequence may impac

• As previously discussed even though

  2022-08-19

  

  As previously discussed, even though glucose is the major fuel of the brain, neuronal cells may use alternative fuels such as ketone bodies in metabolically challenging situations in which glucose availability is limited [6]. Ketogenesis takes place mainly in the liver, although astrocytes can also

• It was reported that GPR is expressed on

  2022-08-19

  

  It was reported that GPR120 is expressed on macrophages in adipose tissue (Oh et al., 2010). Whether GPR120-positive Iodoacetyl-LC-Biotin in human and rat pancreas belongs to macrophages was studied. CD68 is a transmembrane glycoprotein that is highly expressed by human monocytes and tissue macropha

• Some studies show that testosterone may be

  2022-08-18

  

  Some studies show that testosterone may be involved in regulating cell proliferation and its stimulating effect has been proved in castrated rats (Wainwright et al., 2011), but not in mice and meadow voles (Ormerod and Galea, 2003; Benice and Raber, 2010). However, the seasonal difference in cell pr

• Experimental section br Results and discussion br Conclusion

  2022-08-18

  

  Experimental section Results and discussion Conclusion In summary, we have developed a fluoresence method to sensitively detect hAAG on the basis of TdT-activated Endo IV-assisted hyperbranched amplification. This method shows the following advantages: (1) the combination of TdT-mediated exte

• Hippo signaling is an emerging tumor suppressor pathway that

  2022-08-18

  

  Hippo signaling is an emerging tumor suppressor pathway that plays key roles in normal physiology and tumorigenesis through the regulation of cellular proliferation and survival [4]. In humans, YAP is over-expressed as a result of genomic amplification of the 11q22 locus in a wide spectrum of human

• In this study we present the synthesis and structure

  2022-08-18

  

  In this study, we present the synthesis and structure–activity studies of a structurally distinct series possessing high potency and selectivity in HEK cell lines together with a potentially promising overall biopharmacological profile. Focusing on creating sufficient structural dissimilarity with g

• br Acknowledgements br Introduction Aminoacyl tRNA

  2022-08-18

  

  Acknowledgements Introduction Aminoacyl-tRNA synthetases catalyze the formation of an ester bond between an amino transferases and the 3′ end of a tRNA in a two-step reaction. First, the amino acid is activated and an enzyme-bound adenylate intermediate is formed. Then, the amino acid is tran

• br The concept of the

  2022-08-18

  

  The concept of the axo-myelin ‘synapse’ Axons can release glutamate in a Ca+-dependent and independent manner (reviewed in [13,69]). Glutamate released from axons activates GluRs located in myelin, a feature that gave rise to the idea of the axo-myelin ‘synapse’ by analogy with classical synaptic

• There are human genes in

  2022-08-18

  

  There are 12 human genes in the SLC5A family, and 6 of these are expressed in human heart (Table 2). Little is known about SGLT proteins in the heart. Zhou et al. [56] reported the presence of SGLT1 mRNA in the human heart. Researchers have found that levels of SGLT1 mRNA in heart are approximately

• SB408124 In this present study the availability of commercia

  2022-08-18

  

  In this present study, the availability of commercial GLUT and SGLT SB408124 directed against different epitopes, enabled us to screen for members of the SGLT family and compare the expression patterns of GLUTs and SGLTs in the different regions of the rat lens. Based on these regional and subcellu

• It was previously proposed that

  2022-08-18

  

  It was previously proposed that glucagon acts in the liver, in which a signal is produced and relayed to the VEGFR Tyrosine Kinase Inhibitor II via vagal nerves [8], [36], [37]. The concept that the liver is the primary target site was supported by the studies reporting that the glucagon receptor i

• br Introduction HH GLI signaling is

  2022-08-18

  

  Introduction HH-GLI signaling is one of the major pathways involved in both normal and neoplastic development [[1], [2], [3], [4]]. Inappropriate activation of this pathway has been linked to cancer, including medulloblastoma, rhabdomyosarcoma, basal cell carcinoma and cancers of the lung, stomac

• The regulation of casein expression during lactation

  2022-08-18

  

  The regulation of casein expression during lactation is a complex process involving a coordinated response at several levels. A variety of hormones are known to play roles in lactogenesis, such as prolactin (PRL), insulin, and hydrocortisone, and there is now increasing evidence that growth factors,

• br Acknowledgments br Introduction When

  2022-08-18

  

  Acknowledgments Introduction When human red blood cell (hRBC) membranes are depolarized, either as intact BKM120 suspended in depolarizing (low Cl−) Ringers or under voltage clamp conditions using excised inside-out patches, they respond by opening a nonselective voltage-dependent cation (NSVD

15294 records 363/1020 page Previous Next First page 上5页 361362363364365 下5页 Last page