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br OPG RANK and RANKL contribute
2019-04-29
OPG, RANK and RANKL contribute to the vicious cycle established between tumour eukaryotic initiation factor and bone microenvironment: evidences for sarcomas and carcinomas In bone microenvironment, OPG/RANK/RANKL molecular triad is not solely expressed by bone cells. Whether OPG is considered as
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In this work we confirmed that MDA
2019-04-29
In this work we confirmed that MDA-MB-231 breast cancer eph receptor are sensitive to AT-406 by restoring apoptosis in this cell line at nanomolar concentrations [11]. It was previously shown by us and other authors that RANK (receptor activator of NF-κB) is expressed in vitro by several human bre
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br Discussion Both hypokalemia and TC are known to
2019-04-29
Discussion Both hypokalemia and TC are known to cause QT prolongation and TWA. In spite of prolonged hypokalemia, the alternans of J-wave amplitude and TWA changed dramatically with the time course of the patient׳s recovery from myocardial stunning, which suggested that hypokalemia was not likely
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The cardiac GP are a collection of
2019-04-29
The cardiac GP are a collection of autonomic nervous systems comprising both afferent and efferent as well as sympathetic and parasympathetic fibers [10,11]. Radiofrequency catheter ablation eliminates the most elementary level of vagal innervation by destroying the visceral efferent limb of the par
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Introduction Atrial fibrillation AF is the most common cardi
2019-04-29
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it commonly occurs after cardiac surgery. AF is often associated with stroke, congestive heart failure, and myocardial infarction, all of which contribute to the increase in the length of hospital stay, higher medical
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Despu s de la firma de un
2019-04-29
Después de la firma de un eventual acuerdo de paz con todos los grupos guerrilleros incluidas las farc-ep y el eln, se finaliza con la etapa intermedia del conflicto armado en Colombia y se inicia una nueva etapa, caracterizada por el tránsito del conflicto al posconflicto conocida como la etapa fin
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Myoseverin Acute kidney injury is a common
2019-04-28
Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid
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Algunos estudiosos de Pacheco han asimilado la dial
2019-04-28
Algunos estudiosos de Pacheco han asimilado la dialéctica de los elementos con una circularidad que subraya la coincidencia entre el fin y el comienzo, pensando no solo en el eterno retorno característico de Heráclito, sino también en la cosmología azteca. Pura López Colomé, por ejemplo, analiza el
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Toda la semblanza que Vigil hace de la
2019-04-28
Toda la semblanza que Vigil hace de la monja está dirigida gallic acid mostrar la capacidad intelectual y filosófica de ésta, su excepcionalidad y la injusticia de la época en la que le tocó vivir, y que no le permitió su pleno desarrollo. La es para éste un “documento precioso” en el cual se puede
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br Recent changes in act to
2019-04-28
Recent changes in act to further the burden of discrimination towards lesbian, gay, bisexual, and transgender (LGBT) populations. As of 2014, 81 jurisdictions criminalise consensual sexual conduct between adults of the same sex, 38 of which are in Africa. Homosexuality is a capital offence in five
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order Caspase-3/7 Inhibitor Esa es la interconexi n entre el
2019-04-28
Esa es la interconexión entre el capital, entendido como forma social, y el universo de lo político, que no significa una vinculación mecánica entre dos objetos diferentes, sino una compleja relación en el interior de una misma forma social. Es en las paradojas de la globalización, donde se advierte
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A trav s de la figura del
2019-04-28
A través de la figura del marxista argentino Aníbal Ponce, en el número inicial de la revista, Oscar Terán presentó unas breves reflexiones sobre el exilio. Imposibilitado de tematizar la nación por su adscripción al universo discursivo de la tradición intelectual liberal-positivista de la llamada “
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Megacities are also linked with increased instances of viole
2019-04-28
Megacities are also linked with increased instances of violent victimisation and gender-based violence. Urban women, in many instances the victims of violence, are at a higher risk of contracting sexually transmitted infections and HIV than their rural counterparts. The increased instances of violen
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erbb2 inhibitor In an effort to determine
2019-04-28
In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi
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br Conflict of Interest br Acknowledgments br
2019-04-28
Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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